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Tamoxifen did eventually receive marketing approval as a fertility treatment, but the class of compounds never proved useful in human contraception.

 

J Pediatr. 2003 Jul;143(1):60-6. Tamoxifen treatment for precocious puberty in McCune-Albright syndrome: a multicenter trial. Eugster EA, Rubin SD, Reiter EO, ...

 

Dev Dyn. 2006 Sep;235(9):2603-12. Kinetics of tamoxifen-regulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows ...

 

[ More results from www.ncbi.nlm.nih.gov ]

Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Michalides R, Griekspoor A, Balkenende A, ...

 

Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women with hormone receptor-positive breast cancer: the ...

 

[ More results from www.ncbi.nlm.nih.gov ]

The selective estrogen receptor modulator tamoxifen has been used for more than three decades to treat metastatic and early-stage receptor-positive breast ...

 

Anastrozole (Arimidex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results ...

 

[ More results from www.ncbi.nlm.nih.gov ]

MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and ...

 

Clinical trials conducted in Western countries have shown that aromatase inhibitors are associated with better disease-free survival (DFS) than tamoxifen in ...

 

[ More results from www.ncbi.nlm.nih.gov ]

Tamoxifen has been a mainstay of adjuvant therapy for breast cancer for many years. We sought to determine if genetic variability in the tamoxifen metabolic ...

 

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